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FDA Changes Epinephrine Label, Revises Dosage Instructions for Anaphylaxis, Cardiac Arrest

An important change is being made to the label of epinephrine. Traditionally, the two doses of epinephrine have been labeled and called 1:1000 (used traditionally for anaphylaxis) and 1:10,000 (used for cardiac arrest). There has often been confusion between the two doses and uses. Now, the labels will be changed to 1 mg/mL (1:1000) and 0.1 mg/mL (1:10,000). It is hoped that this change will decrease or eliminate the confusion. The labeling of epinephrine combined with other drugs (such as lidocaine) will not change.

In addition, isoproterenol 1:5000 will now be labeled 0.2 mg/mL, and neostigmine 1:1000 will be labeled as 1 mg/mL.

The post FDA Changes Epinephrine Label, Revises Dosage Instructions for Anaphylaxis, Cardiac Arrest appeared first on ACEP Now.


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